Certification of analysis
The quality marker for hot water extracted Agaricus blazei Murrill (ABM) is beta-glucan. ABM extract should be based on the fruiting body of the mushroom.
The quality markers for CCCE are beta-glucan and cordycepin. Three different types of beta-glucan are combined in this formula, all extracted from the fruiting body of the specific mushrooms. The cordycepin is from Cordyceps militaris fruiting bodies.
The main quality markers for Chaga are beta-glucan, polyphenols (anti-oxidants) and triterpenes (i.p. betulinic acid).
A Chaga extract should ideally be dual extracted and based on the wild-harvested sclerotia of this mushroom. Never cultivated Chaga ! (which is beige instead of dark-brown/black).
The main quality markers for Cordyceps are adenosine, cordycepin and other nucleosides such as uridine.
Beta-glucan is useful of course, but it is not Cordyceps-specific and it is not responsible for the Cordyceps-specific properties.
The main quality marker for hot water extracted Maitake is beta-glucan.
Maitake contains a unique type of beta-glucan. In line with the research a Maitake extract should be based on the fruiting body of the mushroom.
LION’S MANE L+
Lion’s Mane covers two therapeutic spectra.
• Hot water extracts are very useful for general health and the metabolic system. The main quality marker is beta-glucan and it should be based on the fruiting body.
• Alcohol extracts are very useful for nootropic effects (slowing down the effects of age on cognition and improving the production of NGF / BDNF). The main quality markers are erinacines* and hericenones*(these compounds belong to the group of terpenes) and polyphenols. The deep layer** cultivated mycelia are the main source of these compounds (4 – 8 times more than the fruiting body)
• Dual extracts are a compromise of those two; the water-solubles are diluted by the alcohol-solubles and vice versa. This can probably be compensated by at least doubling or tripling the dosage. Mycelia should be included because they are the main source of the nootropic potential. Considering that 99% of Lion’s Mane supplements are very poor, quality-wise, better make sure all compounds of interest are specified and guaranteed.
*Hericenones and erinacines can be measured using HPLC-UV-ESI/MS, which is the same method used to isolate and discover those compounds. This method is described in the research papers in detail.
**”deep layer cultivated” means “cultivated in liquid” as opposed to rice/grains. The advantage is that there is no left-over substrate in the final product, it is pure mycelium, starch-free. This method is only used in Asia.
TURKEY TAIL P S P – 5 0
The quality marker for hot water extracted Turkey Tail is beta-glucan.
Turkey Tail contains two types of beta-glucan, which are in part linked to peptides to form bioactive glyco-proteins / proteoglycans. To be in line with the research a Turkey Tail extract should preferably be based on a specific deep layer* cultivated mycelium strain (COV-1) of the mushroom.
*”deep layer cultivated” means “cultivated in liquid” as opposed to rice/grains. The advantage is that there is no left-over substrate in the final product, it is pure mycelium, starch-free. This method is only used in Asia.
The quality markers for Reishi are beta-glucan and in particular triterpenes. Reishi should always be dual extracted (otherwise no triterpenes will be present) and the extract should be based on the fruiting body.
Reishi beta-glucan is in part linked to peptides to form bioactive glyco-proteins / proteoglycans.
SHILAJIT . MUMIJO
The main quality markers for Shilajit are humic and fulvic acids.
A globally accepted standard has been developed to quantify these compounds (AOAC-validated). There are other methods which result in high percentages but these are not accurate.